colostrum doplňky stravy a pleťová kosmetika s colostrem
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Zažívací problény, trávicí trakt a colostrum

Playford RJ, Macdonald CE, Johnson WS; American Journal of Clinical Nutrition, Vol. 72, No. 1, 5-14, July 2000. Colostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders.

Playford RJ, Floyd DN, Macdonald CE, Calnan DP, Adenekan RO, Johnson W, Goodlad RA, Marchbank T., Gut. 1999 May;44(5):653-8. Related Articles, Links, Bovine colostrum is a health food supplement which prevents NSAID induced gut damage. University Division of Gastroenterology, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK. Pluske, JR, Morel, PCH. Increasing weaner pig productivity in New Zealand pig herds. Factors associated with grower herd performance in three New Zealand pig farms (1999). Piglets fed a liquid supplement with colostrum powder had a marked increase in villi height in the lumen of the small intestine, indicating greater digestion and absorption of nutrients. There were also an increased number of immune cells in the villi, indicating enhanced immune competency.

Lissner R; Schmidity H; Karch H; A standard immunoglobulin preparation produced from bovine colostrum shows antibody reactivity and neutralization activity against Shiga-like toxins and EHEC-hemolysin of Escherichia coli 0157:H7 Biotest Pharma GmbH, Dreieich, Germany, Infection 1996, Sep-Oct-;24[5]:378-83

Dluholucky, S et. Al., 1980, Archives of Disease in Childhood, 55, pp 458-460; 1980; Antimicrobial activity of colostrums after the administration of inactive Escherichia Coli oral vaccine to expectant mothers: Mothers developed immune factors that develop on mucosal sources that enter blood serum and concentrate in expectant mothers’ mammary glands. Describes how colostrums may develop immunities.

Bitzan MM; et al, J Infect Dis. April 1998. Inhibition of Hilicobacter pylori and Helicobacter mustelae binding to lipid receptors by bovine colostrum. Results indicate confirmation that colostrum can prevent infection of Helicobacter species bacteria.

Spik, Genevive, et. al. 1983, Immunology, Vol. 35 No 4 pp. 663-670: "Bacteriostasis of a milk-sensitive Strain of E. coli by lmmunoglobulins and Iron-binding Proteins in Association": French doctors showed that a combination of IgG and Lactoferrin in colostrum was bacteriostatic for E. coli.

Dial, Elizabeth J.; et. al. Gastroenterology, 87; 379-85, 1984 A role for Milk Phospholipids in Protection Against Gastric Acid  (Studies in Adult and Suckling Rats). Findings suggest that milk contains potent anti-ulcer activity.

Beth M. Ley, Colostrum and Lactoferrin: Immune system control. p143, 2000. book reference

By the Editors of The Doctors' Prescription for Healthy Living Magazine. The Colostrum Miracle: The Anti-Aging Super Food that can boost immunity and prevent premature aging. (2005) p97.

Zimecki M; Spiegel K; Wlaszczyk A; Cheneau P; Brunel A; et al; Immunoregulatory effects of a nutritional preparation containing bovine lactoferrin taken orally by healthy individual. Institute of Immunology and Experimental Therapy, Polish Academy of Sciences,Wroclaw, Poland. Arch Immunol Ther Exp [Warsz] 1998;46[4]:231-40.

Ishiguro Y; Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis. J Gastroenterol 1999 Feb;34[1]:66-74

Oz, HS, Ray, M, Chen, TS, McClain, CJ. (2004) Efficacy of a transforming growth factor beta 2 containing nutritional support formula in a murine model of inflammatory bowel disease. Journal of the American College of Nutrition 23(3):220-6. Mice with an experimentally-induced inflammatory bowel disease fed a diet rich in transforming growth factor beta-2 (TGF-ß2) gained more weight, did not develop diarrhea or prolapse, had lower pathological scores and lower serum amyloid (SAA). This study supports the use of TGF-ß2 diets in the treatment of Crohn’s disease.

Pironi, L., et al, 1990, Dig Dis Sci, Vol 35(50 p 582-8; 'Relationship between intestinal permeability and inflammatory activity in asymptomatic patients with Crohn's disease.'

Petschow BW; Talbott RD; Batema RP;Ability of lactoferrin to promote the growth of Bifidobacterium spp.in vitro is independent of receptor binding capacity and iron saturation level. J.Med Microbio 11999 Jun;48[6]:541-9

Playford RJ, Boulton R, Ghatei MA, Bloom SR, Wright NA, Goodlad RA. Comparison of the effects of TGF and EGF on gastrointestinal proliferation and hormone release. Digestion 1996;57:362–7.[Medline]

O'Loughlin W, Winter M, Shun A, et al. Structural and functional adaptation following jejunal resection in rabbits: effect of epidermal growth factor. Gastroenterology 1994;107:87–93.[Abstract]

Procaccino F, Reinshagen M, Hoffman P, et al. Protective effect of epidermal growth factor in an experimental model of colitis. Gastroenterology 1994;107:12–7.[Abstract]

Porter SN, Howarth GS, Butler RN. An orally administered growth factor extract derived from bovine whey suppresses breath ethane in colitic rats. Scand J Gastroenterol 1998;33:967–74.[Medline]

Zeeh JM, Procaccino F, Hoffmann P, et al. Keratinocyte growth factor ameliorates mucosal injury in an experimental model of colitis in rats. Gastroenterology 1996;110:1077–83.[Abstract]

Mashimo H, Wu C, Fishman MC, Podolsky DK. Protection and healing of intestinal mucosa: gene-targeted disruption of intestinal trefoil factor impairs defense of mucosal integrity. Gastroenterology 1996;110:A959 (abstr).

Kim, JW, Jeon, WK, Yun, JW, Park, DI, Cho, YK, Sung, IK, Sohn, CI, Kim, BI, Yeom, JS, Park, HS, Kim, EJ, Shin, MS. (2005) Protective effects of bovine colostrum on non-steroidal anti-inflammatory drug induced intestinal damage in rats. Asia Pacific Journal of Clinical Nutrition 14(1):103-7

Bioactive components for the treatment of gastroinstwestinal disorders Author(s): Ghosh S, Playford RJ. Clinical Science (London, England : 1979). 2003 June; 104(6): 547-56. Review.

Deitch, MD, FACS, Edwin A., Arch. Surg,. 1990, Vol 125, The role of Intestinal Barrier Failure and bacterial Translocation in the Development of Systematic Infection and Multiple organ failure. “...increasingly clear that the gastrointestinal tract is not a passive organ...” “... the GI track recognized as having important endocrine, metabolic, immunologic and barrier functions...” “...bacteria/ednotoxin escaping from the gut could lead to systematic infection and disease...” “...studies indicate that one or more three basic pathophysiologic factors appear to be necessary for bacterial translocation to occur.” “Three promoting factors are disruption of the ecologic balance of the... microflora, resulting in overgrowth with certain bacteria, impaired host immune defences, and physical disruption of the gut mucosal barrier.”

Galland, M.D., FACN, Leo, 1995, Townsend Letter for Doctors, Aug.-Sep. Leaky Gut Syndromes: Breaking the Vicious Cycle. “Leaky Gut Syndromes are usually provoked by exposure to substances which damage the integrity of the intestinal mucosa...causes of damage are infectious agents (viral, bacterial and protozoan), 43-46 ethanol, 47-47 and NSAIDs. 20, 49, 50 Hypoxia of the, 51,52 elevated levels of reactive oxygen metabolites, 53 and cytotoxic drugs 54-56 also increased para-cellular permeability.” “Altered intestinal permeability is a key element in the pathogenisis of many different diseases. Hyperpermeability initiates a pancreatic insufficiency and malnutrition occur; each of these increased leakiness of the small bowel. Effective treatment of the Leaky Gut Syndromes requires several components: avoidance of enterotoxic drugs, and allergic foods, elimination of infection or bacterial overgrowth with antimicrobial ad probiotics, and dietary supplementation with trophic nutrients.

Bjarnason, I. Et al, 1984, Lancet, Vol i p 79-82' The leaky gut of alcoholism: the route of entry for toxic compounds'.

Purup, S, Vestergaard, M, Pedersen, O, Sejrsen, K. (2007) Biological activity of bovine milk on proliferation of human intestinal cells. Journal of Dairy Research 74(1):58-65. Bovine milk contains a number of biologically active components that affect growth development of human intestinal tissue. The degree of activity depended on the stage of lactation..

The Colostrum Miracle: The antiaging superfood, can boost immunity and prevent premature aging By the editors of the Doctors' Prescription for Healthy Living Magazine, 2005.

Playford RJ, Marchbank T, Calam J, Hansen FH. EGF is digested to smaller, less active, forms in acidic gastric juice. Gastroenterology 1995;108:92–101.[Abstract]

MacDonald TM, Morant SV, Robinson GC, et al. Association of upper gastrointestinal toxicity of non-steroidal anti-inflammatory drugs with continued exposure: cohort study. BMJ 1997;315:1333–7.[Abstract/Full Text]

Playford RJ, Floyd DN, Macdonald CE, et al. Bovine colostrum is a health food supplement which prevents NSAID-induced gut damage. Gut 1999;44:653–8.[Abstract/Full Text]

Kim, JW, Jeon, WK, Yun, JW, Park, DI, Cho, YK, Sung, IK, Sohn, CI, Kim, BI, Yeom, JS, Park, HS, Kim, EJ, Shin, MS. (2005) Protective effects of bovine colostrum on non-steroidal anti-inflammatory drug induced intestinal damage in rats. Asia Pacific Journal of Clinical Nutrition 14(1):103-7

Hirano M, Iweakiri R, Fujimoto K, et al. Epidermal growth factor enhances repair of rat intestinal mucosa damaged after oral administration of methotrexate. J Gastroenterol 1995;30:169–76.[Medline]

Sonis ST, Lindquist L, Van Vugt A, et al. Prevention of chemotherapy-induced ulcerative mucositis by transforming growth factor beta 3. Cancer Res 1994;54:1135–8.[Abstract]

Howarth GS, Francis GL, Cool JC, Ballard RW, Read LC. Milk growth factors enriched from cheese whey ameliorate intestinal damage by methotrexate when administered orally to rats. J Nutr 1996;126:2519–30.[Medline]

Gordler NM, McGurk M, Aqual S, Prince M. The effect of EGF mouthwash on cytotoxic-induced oral ulceration. Am J Clin Oncol 1995;18:403–6.[Medline]

Purup, S, Vestergaard, M, Pedersen, O, Sejrsen, K. (2007) Biological activity of bovine milk on proliferation of human intestinal cells. Journal of Dairy Research 74(1):58-65. Bovine milk contains a number of biologically active components that affect growth development of human intestinal tissue. The degree of activity depended on the stage of lactation.

Dial EJ.; Hall LR; Serna H; Romero JJ; Fox JG; Lichtenberger LM; Antibiotic properties of bovine lactoferrin on Helicobacter pylori. Department of integrative biology, The University of Texas- Houston Medical School. Dig Dis Sci 1998 Dec: 43[12]: 2750-6.

Playford RJ, Boulton R, Ghatei MA, Bloom SR, Wright NA, Goodlad RA. Comparison of the effects of TGF and EGF on gastrointestinal proliferation and hormone release. Digestion 1996;57:362–7.[Medline]

Playford RJ, Floyd DN, Macdonald CE, Calnan DP, Adenekan RO, Johnson W, Goodlad RA, Marchbank T., Gut. 1999 May;44(5):653-8. Related Articles, Links, Bovine colostrum is a health food supplement which prevents NSAID induced gut damage. University Division of Gastroenterology, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK. Pluske, JR, Morel, PCH. Increasing weaner pig productivity in New Zealand pig herds. Factors associated with grower herd performance in three New Zealand pig farms (1999). Piglets fed a liquid supplement with colostrum powder had a marked increase in villi height in the lumen of the small intestine, indicating greater digestion and absorption of nutrients. There were also an increased number of immune cells in the villi, indicating enhanced immune competency.

Bioactive components for the treatment of gastroinstwestinal disorders Author(s): Ghosh S, Playford RJ. Clinical Science (London, England : 1979). 2003 June; 104(6): 547-56. Review.