Reumatoidní artritída a colostrum
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Zimecki, M, Artym, J. [Therapeutic properties of proteins and peptides from colostrum and milk] Colostrum and milk are rich in peptides and proteins which play an active role in innate immunity. PRP has a variety of immunotropic functions, including the promotion of T cell maturation and inhibition of autoimmune disorders.Post py Higieny i Medycyny Doswiadczalnej 59:309-323 (2005)
Kruzel ML, Actor JK, Boldogh I, Zimecki M; Lactoferrin in health and disease. Lactoferrin, an iron-binding glycoprotein, can be regarded as a cell-secreted mediator that bridges innate and adaptive immune function by regulating target cell response. It is a major pleiotropic mediator that directly assists in the development of T-helper cell polarization. The aim of this mini review is to provide a summary of the most recent work presented at the Lactoferrin Mini symposium at the University of Texas, Health Science Center at Houston, Texas, USA, regarding role of lactoferrin in maintaining immune homeostasis. The data presented here lay emphasis on the significance of lactoferrin in the resolution or progression of the immune responses, thus giving lactoferrin bookend properties in controlling the initial reactions to infectious assault, trauma, and injury. These findings may be critically important in the development of therapeutically relevant protocols. Department of Integrative Biology and Pharmacology, the University of Texas, Health Science Center at Houston, Texas 77030, USA. Postepy Hig Med Dosw (Online). 2007;61:261-7.
Thapa BR; Therapeutic potentials of bovine colostrums. Division of Pediatric Gastroenterology, Postgraduate Institute of Medical Education and Research Chandigarh, India. Indian J Pediatr. 2005 Oct;72(10):849-52.
Zimecki M, Kruzel ML. Milk-derived proteins and peptides of potential therapeutic and nutritive value. J Exp Ther Oncol. 2007;6(2):89-106. Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, 53-114 Wroclaw, Poland.
Jenkins, R. T., et al, 1987, Br J Rheumatol, Vol 26(2) pl0-3-7; 'Increased intestinal permeability in patients with rheumatoid arthritis: a side effect of oral nonsteroidal anti-inflammatory drug therapy.'
Hayashida K, Kaneko T, Takeuchi T, Shimizu H, Ando K, Harada E. Oral administration of lactoferrin inhibits inflammation and nociception in rat adjuvant-induced arthritis. J Vet Med Sci. 2004 Feb;66(2):149-54. Department of Veterinary Physiology, Faculty of Agriculture, Tottori University, Japan.