colostrum doplňky stravy a pleťová kosmetika s colostrem
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Kůže, kožné rány a colostrum

Sporn, et. al., 1983, Science, 219 pp. 1329-31: "Polypeptide Transforming Growth Factors (TGF A & B) and Epithelial Growth Factor Isolated from Bovine Colostrum Used for Wound Healing in Vivo"; Growth factors in bovine colostrum were found to be very effective in promoting wound healing. Implications for trauma, and surgical healing. External and internal applications implied

Noda, et. al., 1984, Gann, Vol. 75, 109-1 12. Japanese researchers discovered that Transforming growth Factors A and B (TGF A & B) in bovine colostrum were involved in normal cellular activities such as embryonic development, cell proliferation, and tissue repair. They also reported it promoted the synthesis and repair of DNA -the master code of the cell.

Allen and Rankin, 1990, PSEBM Vol. 194, Muscle Biology Group, Dept. of Animal Sciences and Physiology, Univ. of Arizona, Tucson, AZ. Reported: A. Fibroblast growth factor (FGF) stimulates proliferation but depresses differentiation of muscle cell growth. B. Insulin like Growth Factor (IGF-1) stimulates both. C. Transforming Growth Factor (TGF-b) slightly depresses proliferation and inhibits differentiation. Conclusion: When administered in combination these factors induce satellite cells to grow, regenerate and proliferate. Following, these cells will fuse with one another or the adjacent muscle fiber thereby increasing myonucles numbers for growth and repair. All three Factors found in Bovine Colostrum.

Skottner, Arrhenius-Nyberg, Kanje and Fryklund, 1990, Acta Paediatric Scand. (suppl) 367: 63-66, A. IGF-1 resulted in significant body weight gain and significant bone growth. 6. Topical administration to wounds resulted in more effective healing. C. Stimulated nerve regeneration.

Chaumeil, Liolet, Kogbe, 1994, Adv Exp. Med. Biol. Report of clinical study Vol. 350 pp. 595-599 Reported effective treatment of eye infections with bovine colostrum lactoserum i.e. reduction in glaucoma, scaring after injury or surgery, reduction in eye lesions.

Bhora, et. al. Jour. Surg. Res. 1995 V 59 p 236-44: Effect of growth factors on cell proliferation in human skin.: "The failure of chronic wounds to heal is a major medical problem. Studies suggest an important role for growth factors in promoting wound healing. Conclusion: Fibroblast growth factor IGF-1 and epithelial growth factor are important for wound healing." Treatment implications for trauma and surgical wounds accelerated healing possible.

Bhora, Y, et al. Effect of growth factors on cell proliferation and epithelialization in human skin. Journal of Surgical Research 59(2):236-244 (1995). Fibroblast growth factor (FGF), IGF-1 and epithelial growth factor (EGF) are important factors in healing skin wounds. EGF in particular is capable of initiating epithelial growth.

Sporn, et al. Polypeptide Transforming Growth Factors (TGF A & B) and Epithelial Growth Factor isolated from bovine colostrum used for wound healing in vivo. Science, 219, pp. 1329-31, 1983.

Breese, et. al., Jour. Gerontology (aging) 1991 V 46 p B180-7: Influence of age and long term dietary restriction on IGF-1: "Study of relationship of IGF-1 and lifespan: Demonstrated a decrease in relative IGF-I concentration with age , as well as dietary restriction. Indicates aging associated with reduced levels in plasma IGF-1 and other GH levels." Implications as anti-aging.

Ballard, Neild, Francis et. al., 1982, Journal of Cellular Physiology, 110 pp 249-254. "The Relationship Between the Insulin Content and Inhibitory Effects of Bovine Colostrum on Protean Breakdown": Insulin-like ingredient in bovine colostrum (IgF-I) slows protein breakdown. Protein breakdown was also slowed by addition of colostrum to a cell line known to be unresponsive to insulin, indicating the presence of non-insulin growth factors in bovine colostrum.

Roberts, Sporn, Assoian, et. al., 1986, Procedures of the National Academy of Sciences, Vo1..83, pp. 4167-71: "Transforming Growth Factor Type B: Rapid Induction of Fibrosis and Angiogenisis in Vivo and Stimulation of Collagen Formation in Vitro" Ristow, et al., pp. 5531-5533 Reports BSC-1 growth inhibitor type B transforming factor is a strong inhibitor of thymocyte (T-lymphocyte precursor) proliferation (presence in bovine colostrum confirmed: Noda, 1984)

Skottner, Arrhenius-Nyberg, Kanje and Fryklund, 1990, Acta Paediatric Scand. (suppl) 367: 63-66, A. IGF-1 resulted in significant body weight gain and significant bone growth. 6. Topical administration to wounds resulted in more effective healing. C. Stimulated nerve regeneration.

Francis, Upton, Ballard, MclUeil, 1988, Journal of Biochemistry, Vol. 251: 95-103 (printed in Great Britain): "Insulin-Like Growth Factors 1 & 2 in Bovine Colostrum": Two growth factors similar to insulin were purified from bovine colostrum IgF-I found to be identical to the corresponding human growth factor. In this experiment protein synthesis was increased and protein breakdown was reduced by administration of the bovine colostrum extracts.

Marcotty et. al., Growth Regulation 1991 Longman Group UK: IgF-I from cow colostrum: Characterization: "lgF-I potent stimulator of growth and differentiation of numerous cell types. Bovine sequence identical to Human IgF- I.

Bhora F, Dunkin B, Batzri S, et al. (1995) Effect of growth factors on cell proliferation and epithelialization in human skin. Journal of Surgery Res. 59:236-244.

Gil, Angel, Sanchez-Medina, 1981, Journal of Dairy Research, Vol 48 Vol. pp 35-44. "Acid Soluble Nucleotides of Cow's, etc.": Bovine Colostrum was found to contain seven different nucleotides which are important for normal cell function and repair.