Imunoglobuliny a colostrum
Francis, G. L., et al., Insulin-like growth factors-l (IGF-1) and 2 (IGF-2) in bovine colostrum. Biochem. J. 1988. 251:p. 95-103.
Francis, G. L., et al., Purification and partial sequence analysis of insulin-like growth factor-l (IGF-1) from bovine colostrum. Biochem. J. 1986. 233: p.207-213.
Petschow B, Talbott R. (1994). Reduction in virus-neutralizing activity of a bovine colostrum immunglobulin concentrate by gastic acid and digestive enzymes. Journal of Pediatric Gastroenterology and Nutrition. 19:228-235.
Plettenberg A, Stoehr A, Stellbrink J, Albreacht H, Meigel W. (1993) A preparation from bovine colostrum in the treatment of HIV-positive patients with chronic diarrhea. Clinical Investigator. 71:42-45.
Savilahti E, Tainio VM, Salmenpera L, Arjomaa P, Kallio M, Perheentupa J, Siimes MA. (1991) Low colostral IgA associated with cow's milk allergy. Acta Pediatr Scan. 80:1207-1213.
Selo I, Clement G, Bernard H, et al. (1999) Allergy to bovine B-lactoglobulin: specificity of human IgE to tryptic peptides. Clinical and Experimental Allergy. 29:1055-1063.
Tejada-Simon M, Lee J, Ustunol Z, Pestka J. (1999) Ingestion of yoghurt containing lactobacillus acidophilus and bifidobacterium to potentiate immunoglobulin A responses to cholera toxin in mice. Journal of Dairy Science. 82:649-660.
Tyler J, Stevens B, Hostetler D, Holle J, Denbigh J. (1999) Colostral immunoglobulin concentrations in holstein and guernsey cows. American Journal of Veterinary Research. 60(9):1136-9
Spik, Genevive, et. al. 1983, Immunology, Vol. 35 No 4 pp. 663-670: "Bacteriostasis of a milk-sensitive Strain of E. coli by lmmunoglobulins and Iron-binding Proteins in Association": French doctors showed that a combination of IgG and Lactoferrin in colostrum was bacteriostatic for E. coli.
Brüssow, H., et al. Bovine milk immunoglobulins for passive immunity to infantile rotavirus gastroenteritis. Journal of Clinical Microbiology 25(6):982-986 (1987). Protection against rotavirus, a dangerous pathogen which can cause serious, even fatal diarrhea in infants, can be passed orally through milk or colostrum safely and effectively.
Funatogawa, K, et al. Use of immunoglobulin enriched bovine colostrum against oral challenge with enterohaemorrhagic Eschericia coli O157:H7 in mice. Microbiology and Immunology 46(11):761-766 (2002). Colostrum can prevent infection against food-borne pathogens by preventing them from binding to the intestinal lining.
Khazenson L.B., et al. "[Activity of bovine colostral IgG in the human digestive tract]." Zh Mikrobiol Epidemiol, Immunobiol, 1980;9:101-106.
Palmer, EL, et al. Antiviral activity of colostrum and serum Immunoglobulins A and G. Journal of Medical Virology 5:123-129 (1980). Virus-specific IgA was discovered in colostrum, including anti-polio antibody.
Stephan, W, et al. Antibodies from colostrum in oral immunotherapy. Journal of Clinical Chemistry and Clinical Biochemistry 28:19-23 (1990). An immunoglobulin preparation from pooled bovine colostrum was found to be very effective in treating severe diarrhea, such as often found in AIDS patients.